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Jeffrey Amos edited this page 4 weeks ago
Plenty of stuff packed into this post.
The exception to the rule is the DOT1 household, members of which methylate K79 within the globular region of histone H3 and that are structurally not related to SET-area proteins four - 6 Recent work suggests that SET-domain-containing proteins methylate a couple of proteins in addition to histones (see later)